Hepatitis C virus is a hepato-lymphotropic virus that was also detected in various organs of the body. Furthermore, this form of infection may be presented for the first time by an extrahepatic manifestation. Different extrahepatic manifestations for hepatitis C was described; these extend from strong associations as in mixed cryoglobulinemia to others were anecdotal finding as vitiligo was reported. The list of extrahepatic manifestations of hepatitis C is extending. In this review we tried to shade the light on this expanding list.