Afro-Egypt J Infect  Endem  Dis  2015 December ; 5(4):235

Study of Fibro Q Index as a Non invasive Method to Predict Liver Fibrosis in Chronic Hepatitis C

Nouh MA, El Sebaey HM,Shehab El-Deen SA ,Allam SAA

Tropical Medicine Department, Faculty of Medicine, Menoufia  University, Egypt.

sherifallam389 @yahoo.com

 

ABSTRACT

Background and study aim : Monitoring of liver fibrosis progression is important in patients with chronic hepatitis C .The aim of this study is to verify the usefulness of FibroQ for predicting fibrosis in patients with chronic hepatitis C compared with other noninvasive tests.

Patients and methods: This study included 90 naïve patients with chronic hepatitis C who had undergone percutaneous liver biopsy before treat­ment and 20 healthy volunteers as a control group. FibroQ, aspartate aminotransferase (AST)/ala­nine amino-transferase ratio (AAR), AST to platelet ratio index, cirrhosis discriminates score, age-platelet index (API), Pohl score, FIB-4 index, and Lok’s model were calculated and compared.

Results: FibroQ, FIB-4, AAR, API and Lok's model results increased significantly as fibrosis advanced .FibroQ trended to be superior in predicting significant fibrosis score in chronic hepatitis C compared with other noninvasive tests.

Conclusion: FibroQ is a simple and useful test for predicting significant fibrosis in patients with chronic hepatitis C.