Afro-Egypt J Infect Endem Dis 2014 September ;4(3):149

 

Doxycycline Induced Extensive Esophageal Ulcerations: Case Report and Review of the Literature

 

Abd Elbaser ES

 

Tropical Medicine Department, Faculty of Medicine, Zagazig University, Egypt
dr.sayedsaad79@gmail.com

 

                              

 

ABSTRACT

Drug induced esophageal disease is common. Doxycycline is one of the commonest causes of drug induced esophageal disease. The diagnosis is usually clinical but endoscopy is the gold standard diagnostic modality. Treatment is mainly depending on discontinuation of the offending medication. If left untreated it can have serious consequences like delayed esophageal stricture. A 22-year-old male had been prescribed doxycycline capsules for acne and developed odynophagia. Endoscopy revealed extensive esophageal ulcerations. He was managed symptomatically with proton pump inhibitors and his odynophagia improved over a period of five days. He was discharged with proper advice regarding medication ingestion and proton pump inhibitor for four weeks.